Journal: iScience
Article Title: Ultrasound-targeted microbubble destruction enhances RSL3-induced ferroptosis in anaplastic thyroid carcinoma
doi: 10.1016/j.isci.2026.114993
Figure Lengend Snippet: Characterizations of the RSL3-MBs (A) Microscopic image of RSL3-MBs. Scale bars, 5 μm. (B) Size distribution of the MBs and RSL3-MBs. (C) Zeta potential of MBs and RSL3-MBs ( n = 3 per group; mean ± SEM; and independent samples t test). (D) Size changes of RSL3-MBs within 1.5 h after preparation. (E) Viability of Nthy-ori 3-1 cells incubated with different concentrations of MBs ( n = 5 per group; mean ± SEM; and one-way ANOVA). (F) Viability of Nthy-ori 3-1 cells incubated with different concentrations of RSL3-MBs ( n = 5 per group; mean ± SEM; and one-way ANOVA). (G) HE staining of heart, liver, spleen, lung, and kidney sections at day 12 after injection of MBs and RSL3-MBs. Scale bars, 50 μm.
Article Snippet: The human thyroid follicular epithelial cell line Nthy-ori 3-1 (CL-0817) and the human anaplastic thyroid cancer cell line CAL-62 (CL-0618) were obtained from Procell Life Science & Technology Co., Ltd.
Techniques: Zeta Potential Analyzer, Incubation, Staining, Injection